Anti-IL17RB Polyclonal Antibody
Cat: K009078P
Summary:
| 【Product name】：Anti-IL17RB Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：55540 | 【Swiss Prot】：Q9NRM6 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:200-1000. IHC 1:30-150. | |
| 【Immunogen】：A synthetic peptide of human IL17RB | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor.
Verified picture:
Immunohistochemistry of paraffin-embedded Human breast cancer with IL17RB antibody diluted at 1:100.
Western blot analysis with IL17RB antibody diluted at 1:500;Lane: Human normal liver.