Anti-ATR Polyclonal Antibody
Cat: K009018P
Summary:
| 【Product name】：Anti-ATR Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：545 | 【Swiss Prot】：Q13535 |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:200-1000. | |
| 【Immunogen】：A synthetic peptide of human ATR | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene belongs the PI3/PI4-kinase family, and is most closely related to ATM, a protein kinase encoded by the gene mutated in ataxia telangiectasia. This protein and ATM share similarity with Schizosaccharomyces pombe rad3, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This kinase has been shown to phosphorylate checkpoint kinase CHK1, checkpoint proteins RAD17, and RAD9, as well as tumor suppressor protein BRCA1.
Verified picture:
Western blot analysis with ATR antibody diluted at 1:500;Lane: K-562,HL-60,MCF7,PC-3M-IE8,A549.