Anti-Histone H3 Polyclonal Antibody
Cat: K106623P
Summary:
| 【Product name】：Anti-Histone H3 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：8350/8351/8352/8353/8354/8355/8356/8357/8358/8968 | 【Swiss Prot】：P68431/P06353 |
| 【Tested applications】：WB;IHC | |
| 【Recommended dilution】：WB 1:500-2000. IHC 1:25-100. | |
| 【Immunogen】：A synthetic peptide of human Histone H3 | |
| 【Public Immunogen Range】：86-136/136aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Verified picture:
Western blot analysis with Histone H3 antibody diluted at 1:1000;Lane: Mouse liver,Mouse testis.
Immunohistochemistry of paraffin-embedded Human colorectal cancer with Histone H3 antibody diluted at 1:50.
Immunohistochemistry of paraffin-embedded Human breast cancer with Histone H3 antibody diluted at 1:50.
Immunohistochemistry of paraffin-embedded Human colorectal cancer with Histone H3 antibody diluted at 1:50.
Immunohistochemistry of paraffin-embedded Human pancreatic cancer with Histone H3 antibody diluted at 1:50.