Anti-HSP90 Polyclonal Antibody
Cat: K106581P
Summary:
| 【Product name】：Anti-HSP90 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：3320 | 【Swiss Prot】：P07900 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:500-2000. IF 1:50-200. | |
| 【Immunogen】：Recombinant protein of human HSP90 | |
| 【Public Immunogen Range】：266-458aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation.Antagonizes STUB1-mediated inhibition of TGF-beta signaling via inhibition of STUB1-mediated SMAD3 ubiquitination and degradation
Verified picture:
Western blot analysis with HSP90 antibody diluted at 1:1000;Lane: HeLa,HepG2,293T,NIH3T3,Raw264.7.
Immunofluorescence analysis of NIH3T3 cells using HSP90AA1 antibody diluted at 1:50.