Anti-HDAC1 Polyclonal Antibody
Cat: K007507P
Summary:
| 【Product name】：Anti-HDAC1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：3065 | 【Swiss Prot】：Q13547 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:500-2000. IHC 1:25-100. | |
| 【Immunogen】：A synthetic peptide of human HDAC1 | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
Verified picture:
Immunohistochemistry of paraffin-embedded Human lung cancer with HDAC1 antibody diluted at 1:50.
Western blot analysis with HDAC1 antibody diluted at 1:1000;Lane: 293T,HeLa,HepG2,MCF7,Mouse thymus,Rat testis.