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Anti-FOXO1 Polyclonal Antibody - Biotin
Cat: K007489P - Biotin
Summary:
【Product name】:Anti-FOXO1 Polyclonal Antibody - Biotin 【Source】:Rabbit
【Isotype】:IgG 【Purification】:Affinity purification
【Gene ID】:2308 【Swiss Prot】:Q12778
【Tested applications】:WB ELISA IHC ICC
【Recommended dilution】:WB 1:50-200. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200. IF 1:50-200
【Immunogen】:A synthetic peptide of human FOXO1
【Storage】:Store at -20℃. Avoid freeze / thaw cycles.
Background:
This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma. Interacts with LRPPRC. Interacts with RUNX2; the interaction inhibits RUNX2 transcriptional activity and mediates the IGF1/insulin-dependent BGLAP expression in osteoblasts Interacts with PPP2R1A; the interaction regulates the dephosphorylation of FOXO1 at Thr-24 and Ser-256 leading to its nuclear import.
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