Anti-EDNRB Polyclonal Antibody
Cat: K007424P
Summary:
| 【Product name】：Anti-EDNRB Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：1910 | 【Swiss Prot】：P24530 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:500-2000. IHC 1:10-100. | |
| 【Immunogen】：A synthetic peptide of human EDNRB | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Verified picture:
Immunohistochemistry of paraffin-embedded Human cervical cancer with EDNRB antibody diluted at 1:50.
Western blot analysis with EDNRB antibody diluted at 1:1000;Lane: HeLa,Mouse brain,MCF7,SW480.