Anti-NPPB Polyclonal Antibody - SAlexa Fluor 750
Cat: K007390P - SAlexa Fluor 750
Summary:
| 【Product name】：Anti-NPPB Polyclonal Antibody - SAlexa Fluor 750 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：4879 | 【Swiss Prot】：P16860 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:25-100. | |
| 【Immunogen】：A synthetic peptide of human NPPB | |
| 【Public Immunogen Range】：67-100aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis.
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