Anti-EIF2S1 Polyclonal Antibody
Cat: K007364P
Summary:
| 【Product name】：Anti-EIF2S1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：1965 | 【Swiss Prot】：P05198 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:500-2000. IHC 1:10-100. | |
| 【Immunogen】：A synthetic peptide of human EIF2S1 | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).
Verified picture:
Immunohistochemistry of paraffin-embedded Human tonsil tissue with EIF2S1 antibody diluted at 1:50.
Western blot analysis with EIF2S1 antibody diluted at 1:1000;Lane: NIH3T3,Jurkat,HeLa.