Anti-MT-CO2 Ponoclonal Antibody
Cat: K006616P
Summary:
| 【Product name】：Anti-MT-CO2 Ponoclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：17709 | 【Swiss Prot】：P00405 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:500-2000. IHC 1:100-500. | |
| 【Immunogen】：A synthetic peptide corresponding to a sequence within amino acids 100-200 of mouse MT-CO2 (NP_904331.1). | |
| 【Public Immunogen Range】：101-200aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII, ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII and cytochrome c oxidase (complex IV, CIV, that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS are transferred via the dinuclear copper A center (CU(A of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC formed by heme A3 and copper B (CU(B. The BNC reduces molecular oxygen to 2 water molecules using 4 electrons
Verified picture:
Western blot analysis with MT-CO2 antibody diluted at 1:1000;Lane: Mouse liver Mouse heart Mouse kidney Rat liver Rat kidney.
Immunohistochemistry of paraffin-embedded rat lung using MT-CO2 antibody at dilution of 1:100 (x40 lens).
Immunohistochemistry of paraffin-embedded mouse brain with MT-CO2 antibody diluted at 1:75.