Anti-NBN Polyclonal Antibody
Cat: K005401P
Summary:
| 【Product name】：Anti-NBN Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：4683 | 【Swiss Prot】：O60934 |
| 【Tested applications】：IF,WB | |
| 【Recommended dilution】：WB 1:500-2000. IF 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human NBN | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.
Verified picture:
Immunofluorescence analysis of U2OS cells using NBN antibody diluted at 1:100.