Anti-HAVCR2 Polyclonal Antibody
Cat: K003383P
Summary:
| 【Product name】：Anti-HAVCR2 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：84868 | 【Swiss Prot】：Q8TDQ0 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:500-1000.IHC 1:50-200 | |
| 【Immunogen】：Recombinant protein of human HAVCR2 | |
| 【Public Immunogen Range】：22-202aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.
Verified picture:
Western blot analysis with HAVCR2 antibody diluted at 1:700;Lane: U-937 Mouse spleen Mouse lung Mouse brain.
Immunohistochemistry of paraffin-embedded colorectal cancer��hu�� using HAVCR2 antibody at dilution of 1:100 (x100 lens��x200 lens).
Immunohistochemistry of paraffin-embedded human lung cancer with HAVCR2 antibody diluted at 1:100.