Anti-EIF6 Polyclonal Antibody
Cat: K003007P
Summary:
| 【Product name】：Anti-EIF6 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：3692 | 【Swiss Prot】：P56537 |
| 【Tested applications】：IF,WB | |
| 【Recommended dilution】：WB 1:500-2000. IF 1:50-200. | |
| 【Immunogen】：Recombinant protein of human EIF6 | |
| 【Public Immunogen Range】：1-245aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits. Multiple non-protein coding transcript variants and variants encoding two different isoforms have been found for this gene.
Verified picture:
Immunohistochemistry of paraffin-embedded liver cancer(hu) using EIF6 antibody at dilution of 1:100 (x100 lens��x200 lens).
Immunofluorescence analysis of MCF7 cell using EIF6 antibody. Blue: DAPI for nuclear staining.
Western blot analysis with EIF6 antibody diluted at 1:1000;Lane: U-251MG HeLa 293T HepG2 K-562.