Anti-Casp8 Polyclonal Antibody
Cat: K002200P
Summary:
| 【Product name】：Anti-Casp8 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：12370 | 【Swiss Prot】：O89110 |
| 【Tested applications】：IF,WB | |
| 【Recommended dilution】：WB 1:500-1000. IF 1:50-200. | |
| 【Immunogen】：Recombinant protein of mouse Casp8 | |
| 【Public Immunogen Range】：4-480aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene is part of a family of caspases, aspartate-specific cysteine proteases well studied for their involvement in immune and apoptosis signaling. This protein, an initiator of apoptotic cell death, is activated by death-inducing tumor necrosis family receptors and targets downstream effectors. In mouse deficiency of this gene can cause embryonic lethality. This protein may have a role in embryogenesis. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
Verified picture:
Western blot analysis with Casp8 antibody diluted at 1:1000;Lane: THP-1 cells.
Immunofluorescence analysis of HeLa cells using Casp8 antibody diluted at 1:100.