Anti-NME1 Polyclonal Antibody
Cat: K001637P
Summary:
| 【Product name】：Anti-NME1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：4830 | 【Swiss Prot】：P15531 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:500-1000. IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human NME1 | |
| 【Public Immunogen Range】：77-177aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.
Verified picture:
Immunohistochemistry of paraffin-embedded pancreatic cancer(hu) using NME1 antibody at dilution of 1:100 (x100 lens��x200 lens).
Immunofluorescence analysis of A549 cell using NME1 antibody. Blue: DAPI for nuclear staining.
Immunohistochemistry of paraffin-embedded Mouse kidney with NME1 antibody diluted at 1:100.