Anti-XRCC6 Monoclonal Antibody
Cat: K001440M
Summary:
| 【Product name】：Anti-XRCC6 Monoclonal Antibody | 【Source】：Mouse |
| 【Isotype】：IgG2b | 【Purification】：Affinity purification |
| 【Gene ID】：2547 | 【Swiss Prot】：P12956 |
| 【Tested applications】：WB,IF,ICC | |
| 【Recommended dilution】：WB 1:500-1000. IF 1:50-200. ICC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human XRCC6 | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa.The complex functions as a single-stranded DNA-dependent ATP-dependent helicase.The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair,transposition,and V(D)J recombination.High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.[provided by RefSeq,Jul 2008]
Verified picture:
Western blot analysis with XRCC6 antibody diluted at 1:1000;Lane: A549,Jurkat,Raji,MCF7,HeLa.
Immunofluorescence analysis of HeLa cells using XRCC6 antibody diluted at 1:100.