Anti-GSDMD Monoclonal Antibody - SAlexa Fluor 647
Cat: K011506M - SAlexa Fluor 647
Summary:
| 【Product name】：Anti-GSDMD Monoclonal Antibody - SAlexa Fluor 647 | |
| 【Isotype】：IgG2a | 【Purification】：Affinity purification |
| 【Gene ID】：79792 | 【Swiss Prot】：P57764 |
| 【Tested applications】：FC ICC IF | |
| 【Recommended dilution】：Flow-Cyt 1:50-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：Recombinant protein of human GSDMD | |
| 【Public Immunogen Range】：135-484aa | |
| 【Storage】：Store at -20℃.Avoid freeze/thaw cycles. | |
Background:
VGSDMD is a member of the gasdermin family.Members of this family appear to play a role in regulation of epithelial proliferation.GSDMD has been suggested to act as a tumor suppressor.Recently GSDMD is identified as a new component of inflammasomes and it is an executor of pyroptosis and required for interleukin-1β secretion.Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.
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