Anti-HMGB1 Monoclonal Antibody - HRP
Cat: K011504M - HRP
Summary:
| 【Product name】：Anti-HMGB1 Monoclonal Antibody - HRP | |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：3146 | 【Swiss Prot】：P09429 |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:500-2000. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human HMGB1 | |
| 【Storage】：Store at -20℃.Avoid freeze/thaw cycles. | |
Background:
High mobility group (HMG) proteins 1 and 2 are ubiquitous non-histone components of chromatin.Evidence suggests that the binding of HMG proteins to DNA induces alterations in the DNA architecture including DNA bending and unwinding of the helix.HMG proteins synergize with Oct-2 members of the NFκB family ATF-2 and c-Jun to activate transcription.
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