Anti-HDAC1 Polyclonal Antibody - Biotin
Cat: K115850P - Biotin
Summary:
| 【Product name】：Anti-HDAC1 Polyclonal Antibody - Biotin | |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：3065 | 【Swiss Prot】：Q13547 |
| 【Observed】：Cow;Chimpanzee;Chicken;Xenopus;laevis | |
| 【Tested applications】：WB ELISA IHC ICC | |
| 【Recommended dilution】：WB 1:50-200. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human HDAC1 | |
| 【Public Immunogen Range】：330-380/482aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Histone acetylation and deacetylation， catalyzed by multisubunit complexes， play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2， it deacetylates p53 and modulates its effect on cell growth and apoptosis.
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