Anti-CXCR4 Polyclonal Antibody - HRP
Cat: K115632P - HRP
Summary:
| 【Product name】：Anti-CXCR4 Polyclonal Antibody - HRP | |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：7852 | 【Swiss Prot】：P61073 |
| 【Observed】：Dog;Chimpanzee;Baboon | |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:500-2000. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human CXCR4 | |
| 【Public Immunogen Range】：1-51/352aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts， hypogammaglobulinemia， infections， and myelokathexis) syndrome. Alternate transcriptional splice variants， encoding different isoforms， have been characterized.
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