Anti-JAG1 Polyclonal Antibody - SAlexa Fluor 350
Cat: K115548P - SAlexa Fluor 350
Summary:
| 【Product name】：Anti-JAG1 Polyclonal Antibody - SAlexa Fluor 350 | |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：182 | 【Swiss Prot】：P78504 |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human JAG1 | |
| 【Public Immunogen Range】：680-730/1218aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1， the latter is involved in signaling processes. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.
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