Anti-IGSF8 Polyclonal Antibody
Cat: K115020P
Summary:
| 【Product name】：Anti-IGSF8 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：93185 | 【Swiss Prot】：Q969P0 |
| 【Observed】：60kDa | |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:1000-3000.IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human IGSF8 | |
| 【Public Immunogen Range】：50-400aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes a member the EWI subfamily of the immunoglobulin protein superfamily. Members of this family contain a single transmembrane domain; an EWI (Glu-Trp-Ile)-motif and a variable number of immunoglobulin domains. This protein interacts with the tetraspanins CD81 and CD9 and may regulate their role in certain cellular functions including cell migration and viral infection. The encoded protein may also function as a tumor suppressor by inhibiting the proliferation of certain cancers. Alternate splicing results in multiple transcript variants that encode the same protein.
Verified picture:
Western blot analysis with IGSF8 antibody diluted at 1:2000;Lane: HMC1,Jurkat,Mouse brain,Rat brain.
Immunohistochemistry of paraffin-embedded Human colorectal cancer with IGSF8 antibody diluted at 1:100.