Anti-GJB1 Polyclonal Antibody
Cat: K114992P
Summary:
| 【Product name】：Anti-GJB1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：2705 | 【Swiss Prot】：P08034 |
| 【Observed】：32/36kDa | |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:1000-3000.IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human GJB1 | |
| 【Public Immunogen Range】：200-250/283aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes a member of the gap junction protein family. The gap junction proteins are membrane-spanning proteins that assemble to form gap junction channels that facilitate the transfer of ions and small molecules between cells. According to sequence similarities at the nucleotide and amino acid levels，the gap junction proteins are divided into two categories，alpha and beta. Mutations in this gene cause X-linked Charcot-Marie-Tooth disease，an inherited peripheral neuropathy. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
Verified picture:
Western blot analysis with GJB1 antibody diluted at 1:2000;Lane: A375,HepG2,HT29,Mouse liver,Rat liver.
Immunohistochemistry of paraffin-embedded Human pancreatic cancer with GJB1 antibody diluted at 1:100.