Anti-HOXB5 Polyclonal Antibody
Cat: K114970P
Summary:
| 【Product name】：Anti-HOXB5 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：3215 | 【Swiss Prot】：P09067 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human HOXB5 | |
| 【Public Immunogen Range】：160-210/269aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in lung and gut development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML) and the occurrence of bronchopulmonary sequestration (BPS) and congenital cystic adenomatoid malformation (CCAM) tissue.
Verified picture:
Immunohistochemistry of paraffin-embedded Human thyroid cancer with HOXB5 antibody diluted at 1:100.
Immunohistochemistry of paraffin-embedded Human liver cancer with HOXB5 antibody diluted at 1:100.