Anti-CD74 Polyclonal Antibody
Cat: K114965P
Summary:
| 【Product name】：Anti-CD74 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：972 | 【Swiss Prot】：P04233 |
| 【Observed】：34kDa | |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:1000-3000. | |
| 【Immunogen】：A synthetic peptide of human CD74 | |
| 【Public Immunogen Range】：150-200/296aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which，when bound to the encoded protein，initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Verified picture:
Western blot analysis with CD74 antibody diluted at 1:2000;Lane: Raji,HepG2,HeLa,Jurkat.