Anti-GZMK Polyclonal Antibody
Cat: K114819P
Summary:
| 【Product name】：Anti-GZMK Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：3003 | 【Swiss Prot】：P49863 |
| 【Observed】：27kDa | |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:1000-3000. | |
| 【Immunogen】：A synthetic peptide of human GZMK | |
| 【Public Immunogen Range】：140-190/264aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize; bind; and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens; usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes.
Verified picture:
Western blot analysis with GZMK antibody diluted at 1:2000;Lane: Lung cancer.