Anti-PGRMC2 Polyclonal Antibody
Cat: K114793P
Summary:
| 【Product name】：Anti-PGRMC2 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：10424 | 【Swiss Prot】：O15173 |
| 【Tested applications】：IHC | |
| 【Recommended dilution】：IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human PGRMC2 | |
| 【Public Immunogen Range】：100-150/223aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Required for the maintenance of uterine histoarchitecture and normal female reproductive lifespan (By similarity. May serve as a universal non-classical progesterone receptor in the uterus (Probable. Intracellular heme chaperone required for delivery of labile; or signaling heme; to the nucleus (By similarity. Plays a role in adipocyte function and systemic glucose homeostasis. In brown fat; which has a high demand for heme; delivery of labile heme in the nucleus regulates the activity of heme-responsive transcriptional repressors such as NR1D1 and BACH1 (By similarity.
Verified picture:
Immunohistochemistry of paraffin-embedded Human renal cancer with PGRMC2 antibody diluted at 1:100.