Anti-IGFBP3 Polyclonal Antibody
Cat: K114778P
Summary:
| 【Product name】：Anti-IGFBP3 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：3486 | 【Swiss Prot】：P17936 |
| 【Observed】：46kDa | |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:1000-3000.IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human IGFBP3 | |
| 【Public Immunogen Range】：80-130/291aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form; it circulates in the plasma; prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants; encoding different isoforms; have been characterized.
Verified picture:
Western blot analysis with IGFBP3 antibody diluted at 1:2000;Lane: HT29,SKOV3,Mouse lung,Mouse kidney.
Immunohistochemistry of paraffin-embedded Human liver cancer with IGFBP3 antibody diluted at 1:100.