Anti-RHEB Polyclonal Antibody
Cat: K114533P
Summary:
| 【Product name】：Anti-RHEB Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：6009 | 【Swiss Prot】：Q15382 |
| 【Observed】：18kDa | |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:500-2000.IHC 1:100-300. | |
| 【Immunogen】：Recombinant protein of human RHEB | |
| 【Public Immunogen Range】：1-185aa | |
| 【Storage】：Store at -20℃. Avoid freeze/thaw cycles. | |
Background:
This gene is a member of the small GTPase superfamily and encodes a lipid-anchored，cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form，and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped，two on chromosome 10 and one on chromosome 22.
Verified picture:
Western blot analysis with RHEB antibody diluted at 1:1000;Lane: U251,U87.
Immunohistochemistry of paraffin-embedded Human testis cancer with RHEB antibody diluted at 1:200.