Anti-PFKM Polyclonal Antibody
Cat: K114680P
Summary:
| 【Product name】：Anti-PFKM Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：5213 | 【Swiss Prot】：P08237 |
| 【Observed】：85kDa | |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:2000-5000. | |
| 【Immunogen】：A synthetic peptide of human PFKM | |
| 【Public Immunogen Range】：120-170/780aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described.[provided by RefSeq, Nov 2009]
Verified picture:
Western blot analysis with PFKM antibody diluted at 1:3000;Lane: MCF7,HeLa,Raji,PC-3,Jurkat.