Anti-AICDA Polyclonal Antibody
Cat: K114318P
Summary:
| 【Product name】：Anti-AICDA Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：57379 | 【Swiss Prot】：Q9GZX7 |
| 【Observed】：25kDa | |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:1000-3000.IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human AICDA | |
| 【Public Immunogen Range】：1-198aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2).
Verified picture:
Western blot analysis with AICDA antibody diluted at 1:2000;Lane: Mouse brain,HL60,THP-1.
Immunohistochemistry of paraffin-embedded Human liver cancer with AICDA antibody diluted at 1:100.