Anti-PRMT5 Polyclonal Antibody
Cat: K113650P
Summary:
| 【Product name】：Anti-PRMT5 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：10419 | 【Swiss Prot】：O14744 |
| 【Observed】：73kDa | |
| 【Tested applications】：WB,IHC | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human PRMT5 | |
| 【Public Immunogen Range】：30-80/637aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes an enzyme that belongs to the methyltransferase family. The encoded protein catalyzes the transfer of methyl groups to the amino acid arginine, in target proteins that include histones, transcriptional elongation factors and the tumor suppressor p53. This gene plays a role in several cellular processes, including transcriptional regulation, and the assembly of small nuclear ribonucleoproteins. A pseudogene of this gene has been defined on chromosome 4. Alternative splicing results in multiple transcript variants encoding different isoforms.
Verified picture:
Western blot analysis with PRMT5 antibody diluted at 1:2000;Lane: HeLa,Vero.
Immunohistochemistry of paraffin-embedded Human breast cancer with PRMT5 antibody diluted at 1:100.
Immunohistochemistry of paraffin-embedded Human colorectal cancer with PRMT5 antibody diluted at 1:100.