Anti-CDK2 Polyclonal Antibody
Cat: K010431P
Summary:
| 【Product name】：Anti-CDK2 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：1017 | 【Swiss Prot】：P24941 |
| 【Tested applications】：ELISA,IHC,WB | |
| 【Recommended dilution】：WB 1:200-1000. IHC 1:15-50. ELISA 1:1000-2000. | |
| 【Immunogen】：Recombinant protein of human CDK2 | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported.
Verified picture:
Western blot analysis with CDK2 antibody diluted at 1:500;Lane: HeLa,Jurkat.
Immunohistochemistry of paraffin-embedded Human cervical cancer with CDK2 antibody diluted at 1:40.