Anti-SMAD3 Polyclonal Antibody
Cat: K010428P
Summary:
| 【Product name】：Anti-SMAD3 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：4088 | 【Swiss Prot】：P84022 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:200-1000. IHC 1:10-100. | |
| 【Immunogen】：A synthetic peptide of human SMAD3 | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD3/SMAD4 complex, activates transcription.
Verified picture:
Western blot analysis with SMAD3 antibody diluted at 1:500;Lane: Kidney cancer.
Immunohistochemistry of paraffin-embedded Human colorectal cancer with SMAD3 antibody diluted at 1:50.