Anti-OTC Polyclonal Antibody
Cat: K010426P
Summary:
| 【Product name】：Anti-OTC Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：5009 | 【Swiss Prot】：P00480 |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:1000-4000. IHC 1:50-100. | |
| 【Immunogen】：Recombinant protein of human OTC | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also.
Verified picture:
Western blot analysis with OTC antibody diluted at 1:3000;Lane: Mouse liver,Rat liver.
Immunohistochemistry of paraffin-embedded Human colorectal cancer with OTC antibody diluted at 1:100.