Anti-Phospho-eIF2α-S51 Polyclonal Antibody - SAlexa Fluor 405
Cat: K010156P - SAlexa Fluor 405
Summary:
| 【Product name】：Anti-Phospho-eIF2α-S51 Polyclonal Antibody - SAlexa Fluor 405 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：1965 | 【Swiss Prot】：P05198 |
| 【Observed】：38kDa | |
| 【Tested applications】：IF,WB,IP | |
| 【Recommended dilution】：WB 1:1000-2000. IP 0.5μg-4μg. IF 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human Phospho-eIF2α-S51 | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation， promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA， EIF2， and GTP. EIF2 is composed of 3 nonidentical subunits， the 36-kD EIF2-alpha subunit (EIF2S1)， the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908)， and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al.， 1987 [PubMed 2948954]).[supplied by OMIM， Feb 2010]
Verified picture: