Anti-CHIT1 Polyclonal Antibody - SAlexa Fluor 660
Cat: K113433P - SAlexa Fluor 660
Summary:
| 【Product name】：Anti-CHIT1 Polyclonal Antibody - SAlexa Fluor 660 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：1118 | 【Swiss Prot】：Q13231 |
| 【Observed】：55kDa | |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:1000-3000. | |
| 【Immunogen】：Recombinant protein of human CHIT1 | |
| 【Public Immunogen Range】：101-450aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase， a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene.
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