Anti-APOOL Polyclonal Antibody
Cat: K113427P
Summary:
| 【Product name】：Anti-APOOL Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：139322 | 【Swiss Prot】：Q6UXV4 |
| 【Observed】：29kDa | |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:2000-5000. IHC 1:25-100. | |
| 【Immunogen】：Recombinant protein of human APOOL | |
| 【Public Immunogen Range】：181-269aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Component of the MICOS complex， a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions， inner membrane architecture， and formation of contact sites to the outer membrane. Specifically binds to cardiolipin (in vitro) but not to the precursor lipid phosphatidylglycerol. Plays a crucial role in crista junction formation and mitochondrial function (PubMed:23704930)， (PubMed:25764979).
Verified picture:
Western blot analysis with APOOL antibody diluted at 1:3000;Lane: K-562,COLO205,HeLa.
Immunohistochemistry of paraffin-embedded Human breast cancer with APOOL antibody diluted at 1:50.