Anti-CYP27A1 Polyclonal Antibody
Cat: K113422P
Summary:
| 【Product name】：Anti-CYP27A1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：1593 | 【Swiss Prot】：Q02318 |
| 【Observed】：58kDa | |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:50-200. | |
| 【Immunogen】：Recombinant protein of human CYP27A1 | |
| 【Public Immunogen Range】：20-370aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol， steroids and other lipids. This mitochondrial protein oxidizes cholesterol intermediates as part of the bile synthesis pathway. Since the conversion of cholesterol to bile acids is the major route for removing cholesterol from the body， this protein is important for overall cholesterol homeostasis. Mutations in this gene cause cerebrotendinous xanthomatosis， a rare autosomal recessive lipid storage disease.
Verified picture:
Western blot analysis with CYP27A1 antibody diluted at 1:2000;Lane: Liver cancer,Mouse liver.
Immunohistochemistry of paraffin-embedded Human thyroid cancer with CYP27A1 antibody diluted at 1:100.
Immunohistochemistry of paraffin-embedded Human stomach cancer with CYP27A1 antibody diluted at 1:100.