Anti-TRPC3/6 Polyclonal Antibody
Cat: K113328P
Summary:
| 【Product name】：Anti-TRPC3/6 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：7222/7225 | 【Swiss Prot】：Q13507/Q9Y210 |
| 【Observed】：100kDa | |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human TRPC3/6 | |
| 【Public Immunogen Range】：170-220/836aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2).
Verified picture:
Western blot analysis with TRPC3/6 antibody diluted at 1:2000;Lane: Mouse brain.
Immunohistochemistry of paraffin-embedded Human colorectal cancer with TRPC3/6 antibody diluted at 1:100.