Anti-LEFTY1/2 Polyclonal Antibody - SAlexa Fluor 555
Cat: K113303P - SAlexa Fluor 555
Summary:
| 【Product name】：Anti-LEFTY1/2 Polyclonal Antibody - SAlexa Fluor 555 | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：10637/7044 | 【Swiss Prot】：O75610/O00292 |
| 【Observed】：37kDa | |
| 【Tested applications】：ICC IF | |
| 【Recommended dilution】：ICC 1:50-200. IF 1:50-200 | |
| 【Immunogen】：A synthetic peptide of human LEFTY1/2 | |
| 【Public Immunogen Range】：120-170/366aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein， which plays a role in left-right asymmetry determination of organ systems during development. This gene is closely linked to both a related family member and a related pseudogene.
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