Anti-CFL2 Polyclonal Antibody
Cat: K113146P
Summary:
| 【Product name】：Anti-CFL2 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Octanoic acid-ammonium sulfate precipitation |
| 【Gene ID】：1073 | 【Swiss Prot】：Q9Y281 |
| 【Observed】：19kDa | |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:1000-3000. IHC 1:50-200. | |
| 【Immunogen】：A synthetic peptide of human CFL2 | |
| 【Public Immunogen Range】：30-80/166aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants.
Verified picture:
Western blot analysis with CFL2 antibody diluted at 1:2000;Lane: Jurkat,HeLa,HepG2,Raji,U251,A549,L-02,SH-SY5Y,Rat brain.
Immunohistochemistry of paraffin-embedded Human liver cancer with CFL2 antibody diluted at 1:100.