Anti-FN3KRP Polyclonal Antibody
Cat: K113073P
Summary:
| 【Product name】：Anti-FN3KRP Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：79672 | 【Swiss Prot】：Q9HA64 |
| 【Observed】：32kDa | |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:1000-3000. | |
| 【Immunogen】：Recombinant protein of human FN3KRP | |
| 【Public Immunogen Range】：1-310aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
A high concentration of glucose can result in non-enzymatic oxidation of proteins by reaction of glucose and lysine residues (glycation). Proteins modified in this way are less active or functional. This gene encodes an enzyme which catalyzes the phosphorylation of psicosamines and ribulosamines compared to the neighboring gene which encodes a highly similar enzyme, fructosamine-3-kinase, which has different substrate specificity. The activity of both enzymes may result in deglycation of proteins to restore their function. Alternative splicing results in multiple transcript variants.
Verified picture:
Western blot analysis with FN3KRP antibody diluted at 1:2000;Lane: U87,U251,MCF7,A549,HepG2,Kidney cancer,Mouse brain,Mouse lung,Rat spleen,Rat testis.