Anti-SMURF1 Polyclonal Antibody
Cat: K010100P
Summary:
| 【Product name】：Anti-SMURF1 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：57154 | 【Swiss Prot】：Q9HCE7 |
| 【Tested applications】：IF,ELISA,WB,IHC | |
| 【Recommended dilution】：WB 1:500-2000. IHC 1:100-500. IF 1:50-200. ELISA 1:5000-10000. | |
| 【Immunogen】：A synthetic peptide of human SMURF1 | |
| 【Public Immunogen Range】：65-170/757aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
E3 ubiquitin-protein ligase that acts as a negative regulator of BMP signaling pathway. Acts by mediating ubiquitination and degradation of SMAD1 and SMAD5, 2 receptor-regulated SMADs specific for the BMP pathway. Promotes ubiquitination and subsequent proteasomal degradation of TRAF family members.
Verified picture:
Immunohistochemistry of paraffin-embedded rat stomach with SMURF1 antibody diluted at 1:400.