Anti-MVP Polyclonal Antibody
Cat: K112985P
Summary:
| 【Product name】：Anti-MVP Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：9961 | 【Swiss Prot】：Q14764 |
| 【Observed】：105kDa | |
| 【Tested applications】：IHC,WB | |
| 【Recommended dilution】：WB 1:5000-8000. IHC 1:25-100. | |
| 【Immunogen】：Recombinant protein of human MVP | |
| 【Public Immunogen Range】：240-590aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene.
Verified picture:
Western blot analysis with MVP antibody diluted at 1:7000;Lane: HeLa,A549,U87,Raw264.7,Rat lung.
Immunohistochemistry of paraffin-embedded Human renal cancer with MVP antibody diluted at 1:50.