Anti-VCAN Polyclonal Antibody
Cat: K112952P
Summary:
| 【Product name】：Anti-VCAN Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：1462 | 【Swiss Prot】：P13611 |
| 【Observed】：270kDa | |
| 【Tested applications】：IHC,WB,ELISA | |
| 【Recommended dilution】：WB 1:2000-5000. IHC 1:25-100. | |
| 【Immunogen】：A synthetic peptide of human VCAN | |
| 【Public Immunogen Range】：2520-2570/3396aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene is a member of the aggrecan/versican proteoglycan family. The protein encoded is a large chondroitin sulfate proteoglycan and is a major component of the extracellular matrix. This protein is involved in cell adhesion, proliferation, proliferation, migration and angiogenesis and plays a central role in tissue morphogenesis and maintenance. Mutations in this gene are the cause of Wagner syndrome type 1. Multiple transcript variants encoding different isoforms have been found for this gene.
Verified picture:
Western blot analysis with VCAN antibody diluted at 1:3000;Lane: PC-3M-IE8.
Immunohistochemistry of paraffin-embedded Human renal cancer with VCAN antibody diluted at 1:50.