Anti-CD86 Polyclonal Antibody
Cat: K010082P
Summary:
| 【Product name】：Anti-CD86 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：56822 | 【Swiss Prot】：O35531 |
| 【Observed】：72/74kDa | |
| 【Tested applications】：ELISA,IF,WB,IHC | |
| 【Recommended dilution】：WB 1:500-2000. ELISA 1:5000-10000. IHC 1:100-500. IF 1:100-500. | |
| 【Immunogen】：A synthetic peptide of rat CD86 | |
| 【Public Immunogen Range】：140-175/313aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011].
Verified picture:
Western blot analysis with CD86 antibody diluted at 1:1000;Lane: HepG2 U937 Rat Spleen Mouse Spleen HL-60.
Immunohistochemistry of paraffin-embedded rat lung tissue with CD86 antibody diluted at 1:200.