Anti-Desmuslin/SYN Polyclonal Antibody
Cat: K010081P
Summary:
| 【Product name】：Anti-Desmuslin/SYN Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：233335 | 【Swiss Prot】：Q70IV5 |
| 【Tested applications】：IHC,IF | |
| 【Recommended dilution】：IHC 1:500-1300. IF 1:500-1300. | |
| 【Immunogen】：Recombinant protein of mouse Desmuslin/SYN | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
SYNM, also named as DMN, KIAA0353 and SYN, belongs to the intermediate filament family. SYNM is a Type-VI intermediate filament (IF) which plays an important cytoskeletal role within the muscle cell cytoskeleton. It forms heteropolymeric IFs with desmin and/or vimentin, and via its interaction with cytoskeletal proteins alpha-dystrobrevin, dystrophin, talin-1, utrophin and vinculin, is able to link these heteropolymeric IFs to adherens-type junctions, such as to the costameres, neuromuscular junctions, and myotendinous junctions within striated muscle cells.
Verified picture:
Immunohistochemistry of paraffin-embedded mouse colon with Desmuslin/SYN antibody diluted at 1:500.
Immunofluorescence analysis of mouse bladder using Desmuslin/SYN antibody diluted at 1:650.