Anti-CCP110 Polyclonal Antibody
Cat: K112540P
Summary:
| 【Product name】：Anti-CCP110 Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：9738 | 【Swiss Prot】：O43303 |
| 【Observed】：130kDa | |
| 【Tested applications】：WB | |
| 【Recommended dilution】：WB 1:1000-3000. | |
| 【Immunogen】：Recombinant protein of human CCP110 | |
| 【Public Immunogen Range】：50-400aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Necessary for centrosome duplication at different stages of procentriole formation. Acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation (PubMed:17719545 PubMed:17681131, PubMed:23486064).Also involved in promoting ciliogenesis. May play a role in the assembly of the mother centriole subdistal appendages (SDA) thereby effecting the fusion of recycling endosomes to basal bodies during cilia formation (By similarity).Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2 (PubMed:16760425).
Verified picture:
Western blot analysis with CCP110 antibody diluted at 1:2000;Lane: 293T,Jurkat,MCF7,HEK293.