Anti-Osteocalcin Polyclonal Antibody
Cat: K010044P
Summary:
| 【Product name】：Anti-Osteocalcin Polyclonal Antibody | 【Source】：Rabbit |
| 【Isotype】：IgG | 【Purification】：Affinity purification |
| 【Gene ID】：632 | 【Swiss Prot】：P02818 |
| 【Tested applications】：ELISA,IF,IHC | |
| 【Recommended dilution】：ELISA 1:5000-10000. IHC 1:100-500. IF 1:100-500. | |
| 【Immunogen】：A synthetic peptide of human Osteocalcin | |
| 【Public Immunogen Range】：21-80/100aa | |
| 【Storage】：Store at -20℃. Avoid freeze / thaw cycles. | |
Background:
Osteocalcin belongs to the osteocalcin/matrix Gla protein family and constitutes 1 to 2% of the total bone protein. It is a 49 amino acid single chain vitamin K dependent protein, made by osteoblasts, and is a major component of the noncollagenous bone matrix. Post translational modification by a vitamin K dependent carboxylase produces three gamma carboxyglutamic acid residues at positions 17, 21 and 24, giving it a high affinity for calcium. It also binds strongly to apatite.
Verified picture:
Immunohistochemistry of paraffin-embedded bone of mouse embryo with Osteocalcin antibody diluted at 1:200.